Une mission de la Caricom se rendra en Haïti ce lundi 27 février 2023.-
2 min readLe Dr Amery Browne, ministre des Affaires étrangères et de la Caricom, a déclaré lors d’un briefing après le Cabinet, au Diplomatic Centre à St Ann’s le jeudi 23/02 2023, qu’une mission spéciale de la Caricom était prévue en Haïti pour parler à toutes les parties (le gouvernement, les partis politiques et la société civile), mais qu’il était prématuré de parler de l’envoi de troupes. Cette décision avait été prise lors de la 44e réunion régulière des chefs de gouvernement de la Caricom aux Bahamas la semaine dernière.
« Une décision clé prise par les chefs de gouvernement de la Caricom aux Bahamas a été de lancer une mission spéciale en Haïti pour avoir des réunions préliminaires avec un certain nombre d’acteurs clés », a-t-il déclaré.
Il a ajouté que la mission était prévue pour le lundi 27 février et que Trinidad et Tobago y participeraient en la personne de l’ancien ministre des Affaires étrangères et de la Caricom, Denis Moses, qui était le haut-commissaire de TT au Canada et qui était fluent en français et avait une certaine expérience avec les acteurs haïtiens, ainsi qu’un membre de la force de défense (TTDF).
« Cette équipe spéciale sera installée aux Bahamas et sera ensuite transportée des Bahamas en Haïti par la force de défense bahamienne. »
Des Canadiens participeraient également à une mission Caricom-Canada pour rencontrer les acteurs haïtiens, ces derniers pourraient également participer à une réunion de suivi en Jamaïque. Browne a déclaré que l’objectif de la mission était de traiter la situation en Haïti le plus rapidement possible.
Interrogé sur l’offre de la Jamaïque d’envoyer des soldats en Haïti, Browne a ajouté : « Je dirais avec tout le respect que la question des troupes et des bottes sur le terrain à ce stade est un peu prématurée. »
Il a précisé que le Premier ministre intérimaire haïtien, Henry, avait participé aux discussions lors de la réunion des chefs de la Caricom. « Ce que la région a clairement indiqué, c’est que la solution à la crise doit être dirigée par les Haïtiens.
Ceux d’entre nous qui sont en périphérie et qui pourraient appeler à l’envoi de troupes, etc., il est un peu prématuré pour nous d’en arriver là.
C’est l’un des domaines qui sera discuté lors de ces consultations avec les acteurs et nous verrons où vont ces discussions. Il s’agit vraiment de mettre le gouvernement d’Haïti tel qu’il se présente actuellement, le service de police national d’Haïti, les éléments de l’opposition et d’autres acteurs clés autour de la table et d’analyser quelles seraient les étapes les plus prudentes à suivre.
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enhance growth hormone release and support muscle
recovery. Although they share a common goal of stimulating the pituitary gland, they differ in structure, mechanism of action, duration of effect, and
sermorelin/ipamorelin blend side effects‑effect profile.
Understanding these distinctions is essential for anyone considering
using either peptide.
—
Ipamorelin vs CJC 1295
Similarities
Growth Hormone Secretagogues: Both peptides act as secretagogues that prompt the
pituitary gland to secrete growth hormone (GH) and insulin‑like growth factor‑1 (IGF‑1).
Short Half‑Lives in Practice: In a typical dosing
regimen, each peptide is administered once or twice daily
because their effects last several hours, not days.
Potential Benefits: Users report improved recovery, increased lean muscle mass, reduced
body fat, better sleep quality, and enhanced joint health.
Differences
Feature Ipamorelin CJC‑1295
Molecular Structure A pentapeptide (five amino acids).
A 33‑amino‑acid peptide with a PEGylated tail that prolongs its presence in the bloodstream.
Half‑Life Roughly 2–3 hours after injection. Approximately 12–24 hours due
to PEGylation, allowing once‑daily dosing.
Receptor Selectivity Highly selective for the growth hormone secretagogue receptor (GHS-R1a) with minimal off‑target activity.
Also targets GHS‑R1a but may have broader interaction because
of its size and PEG component.
Side‑Effect Profile Generally milder; rare reports of increased hunger or
mild water retention. Slightly higher incidence of flushing, tingling, and transient nausea in some users.
Long‑Term Use Impact Limited data; most studies focus on short courses.
More research suggests a risk of desensitization or down‑regulation of
GH receptors if used excessively.
—
What Is Ipamorelin?
Ipamorelin is a synthetic, selective growth hormone secretagogue developed in the 1990s by scientists at
the University of New South Wales. Its design aimed to stimulate
GH release without affecting other hormones such as cortisol or prolactin. The
peptide’s sequence—His-D-Ala-Leu-Lys-Pro—confers a high affinity for GHS‑R1a receptors located
on somatotrophic cells in the pituitary gland.
When Ipamorelin binds to these receptors, it triggers a cascade that results in the secretion of growth
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Key attributes include:
Selective Action: Unlike older secretagogues (e.g., GHRP‑6), Ipamorelin does not elevate cortisol or prolactin levels.
Short Duration: Its rapid clearance limits prolonged exposure to the
hormone system, potentially reducing long‑term side effects.
Ease of Use: Typically administered subcutaneously once
or twice daily; doses range from 100–300 µg per injection.
FAQs: Ipamorelin vs CJC 1295
1. Which peptide is better for cutting versus bulking phases?
Both peptides can be used in either phase, but
the choice often depends on desired GH exposure.
CJC‑1295’s longer half‑life may provide a steadier IGF‑1 surge,
which some users find beneficial during muscle‑building cycles.
Ipamorelin’s shorter action allows for more controlled spikes
that might suit cutting programs where water retention is a concern.
2. Can I combine Ipamorelin with CJC‑1295?
Yes; many protocols pair the two to harness the immediate GH
spike from Ipamorelin and the sustained release from CJC‑1295.
The combination can produce higher peak GH levels while maintaining prolonged IGF‑1 exposure, potentially amplifying anabolic effects.
3. What are common side effects of each peptide?
Ipamorelin: Mild water retention, increased appetite, occasional tingling or flushing, and rare headaches.
CJC‑1295: Similar mild symptoms but with a slightly higher incidence of nausea,
dizziness, and transient joint pain.
Both peptides can cause injection site reactions (redness, swelling) if not administered properly.
Long‑term side effects are poorly documented; caution is advised
for extended use beyond 6–12 weeks.
4. Are there legal restrictions on using these peptides?
In many countries, Ipamorelin and CJC‑1295 are classified as research chemicals or
investigational drugs. They are not approved for human consumption by regulatory agencies such as
the FDA. Athletes risk sanctions if detected in doping tests.
Users should verify local regulations before purchasing or administering.
5. How does each peptide affect sleep?
Both peptides can improve sleep quality by increasing GH secretion during nocturnal hours.
Ipamorelin’s shorter duration may lead to a sharper GH peak just
before bed, while CJC‑1295’s sustained release offers a more prolonged influence on deep sleep stages.
6. What dosage schedules are typical for each peptide?
Ipamorelin: 100–300 µg injected subcutaneously 1–2 times per
day (morning and/or evening).
CJC‑1295: 250–500 µg once daily, often paired with a small dose of Ipamorelin or other secretagogues to
trigger the initial GH surge.
7. Are there contraindications?
Both peptides are generally safe for healthy adults but may pose
risks in individuals with endocrine disorders, liver disease, or kidney impairment.
Pregnant or breastfeeding women should avoid
use entirely. Always consult a healthcare professional before beginning therapy.
—
In summary, Ipamorelin and CJC‑1295 share the common purpose of
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Users should weigh the benefits against potential risks,
adhere to legal guidelines, and consider combining the peptides carefully under professional guidance to optimize results and minimize adverse outcomes.
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